Generation and characterization of Kctd15 mutations in zebrafish.
Potassium channel tetramerization domain containing 15 (Kctd15) was previously found to have a role in early neural crest (NC) patterning, specifically delimiting the region where NC markers are expressed via repression of transcription factor AP-2a and inhibition of Wnt signaling.We used transcription activator-like effector nucleases (TALENs) to